Table 5.
Results of Binary Logistic Regression analysis of CAG (AR2) repeats in relation to covariates (n = 70)
| Variables | Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| Distribution of Genotype in Cases | OR (95% C.I.) | P value | OR (95% C.I.) | P Value | ||
| AR1 (36) (R%, C%)! | AR2 (34) (R%, C%)! | |||||
| Age of onset | ||||||
| Late onset (20) | 8 (40, 22.2) | 22 (44, 64.8) | 1.000 | 0.397 | 1.000 | 0.160 |
| Early onset (50) | 28 (56, 77.8) | 12 (60, 35.2) | 0.786 (0.450, 1.373) | 0.454 (0.151, 1.365) | ||
| Family History | ||||||
| No FH (59) | 30 (50.8, 83.3) | 29 (49.2, 85.3) | 1.000 | 0.763 | 1.000 | 0.523 |
| Having FH (11) | 6 (54.5, 16.7) | 5 (45.5, 14.7) | 0.833 (0.254, 2.731) | 0.637 (0.160, 2.539) | ||
| Stages of Disease | ||||||
| Initial stages (I + II) (23) | 13 (56.5, 36.1) | 10 (43.5, 29.4) | 1.000 | 0.884 | 1.000 | 0.486 |
| Advance stages (III + IV) (47) | 23 (48.9, 63.9) | 24 (51.1, 70.6) | 1.043 (0.589, 1.849) | 1.461 (0.503, 4.243) | ||
| Grade | ||||||
| Lower (I + II) (52) | 29 (55.8, 80.6) | 23 (44.2, 67.6) | 1.000 | 0.350 | 1.000 | 0.120 |
| Higher (III) (18) | 7 (38.9,19.4) | 11 (61.1, 32.4) | 1.571 (0.609, 4.054) | 2.470 (0.781, 7.817) | ||
| Estrogen receptor status | N= 18 | N= 18 | 1.000 | 0.530 | ||
| Positive (10) | 6 (60, 33.3) | 4 (40, 22.2) | 0.667 (0.188, 2.362) | |||
| Negative (26) | 12 (46.2, 66.7) | 14 (53.8, 77.8) | ||||
| Androgen receptor status | N = 20 | N = 26 | 1.000 | |||
| Positive (16) | 8 (50, 40) | 8 (50, 30.7) | 0.668 (0.196, 2.263) | 0.516 | ||
| Negative (30) | 12 (40, 60) | 18 (60, 69.3) | ||||
!:(R%: row percentages, C%: column percentages)