Fig. 3.

Characteristics (productivity and product distribution) of the preengineered strains expressing wild-type ggpps and lps saturation mutagenesis library of: (A) Met593, (B) Tyr700, (C) Ala620, and (D) Tyr700 using lps M593I. In the product distribution charts, gray bars, orange bars, white bars represent proportion of levopimaradiene, abietadiene, and sandaracopimaradiene in the product mixture, respectively. Two toned (white and light gray) bars represent nil production. WT represents the preengineered strain expressing wild-type ggpps and lps.