Table 1.
Patient characteristics at baseline
| Candesartan | CCBs | P value | |
|---|---|---|---|
| N | 27 | 26 | |
| Age, y | 52 ± 13 | 56 ± 8 | 0.1580 |
| Male, n | 23 | 16 | 0.0509 |
| Diabetes, n | 6 | 3 | 0.2987 |
| Prescription of diuretics, n | 4 | 1 | 0.2075 |
| Prescription of statins, n | 3 | 5 | 0.2660 |
| Waist, cm | 91.3 ± 7.9 | 90.9 ± 7.9 | 0.8945 |
| CAVI | 8.7 ± 1.1 | 9.1 ± 0.7 | 0.4175 |
| Plasma BNP, mg/dL | 18.0 ± 16.2 | 13.5 ± 12.2 | 0.6294 |
| UAE, log, (mg/gCr) | 1.14 ± 0.32 | 1.53 ± 0.35 | 0.2007 |
| Max IMT, mm | 0.90 ± 0.32 | 1.20 ± 0.00 | 0.1322 |
| AI, % | 80.1 ± 12.2 | 80.8 ± 14.2 | 0.9001 |
| eGFR, mL/min/1.73 m | 68.4 ± 21.7 | 67.5 ± 18.4 | 0.8947 |
| Serum potassium, mEq/L | 4.2 ± 0.4 | 4.1 ± 0.3 | 0.5683 |
| Serum creatinine, mg/dL | 1.0 ± 0.6 | 0.8 ± 0.3 | 0.3643 |
| Serum uric acid, mg/dL | 6.3 ± 1.2 | 5.6 ± 1.3 | 0.1405 |
| Serum LDL-C, mg/dL | 117 ± 33 | 135 ± 39 | 0.1914 |
| Serum HDL-C, mg/dL | 48 ± 14 | 55 ± 16 | 0.3206 |
| Serum triglycerides, mg/dL | 194 ± 168 | 130 ± 64 | 0.0811 |
| Serum glycated albumin, g/dL | 14.5 ± 1.8 | 13.2 ± 1.1 | 0.2575 |
| Plasma active renin concentration, pg/mL | 8.5 ± 6.8 | 11.8 ± 15.3 | 0.4177 |
Note: Data are mean ± SD.
Abbreviations: CCBs, calcium channel blockers; CAVI, cardio-ankle vascular index; BNP, brain natriuretic peptide; UAE, urine albumin excretion; Max IMT, maximum intima-media thickness of the carotid arteries; AI, augmentation index; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SD, standard deviation.