Table 2.
Clinic and ambulatory BP before and after treatments
|
Candesartan (n = 26) |
CCBs (n = 27) |
Intergroup P value | |||
|---|---|---|---|---|---|
| Baseline | 12 mo | Baseline | 12 mo | ||
| Clinic | |||||
| Systolic BP | 157 ± 23 | 136 ± 13* | 156 ± 21 | 143 ± 9* | 0.7033 |
| Diastolic BP | 99 ± 12 | 87 ± 9* | 95 ± 11 | 87 ± 8* | 0.5969 |
| 24-h ambulatory BP | |||||
| Systolic BP | 143 ± 15 | 120 ± 15 | 140 ± 11 | 124 ± 12 | 0.3509 |
| Diastolic BP | 92 ± 10 | 76 ± 7* | 88 ± 5 | 77 ± 4* | 0.2478 |
| Variability | 20 ± 11 | 16 ± 3 | 20 ± 5 | 19 ± 5 | 0.7718 |
| Nocturnal decrease | 16 ± 7 | 10 ± 13 | 17 ± 11 | 18 ± 13 | 0.5592 |
| Morning surge | 47 ± 23 | 32 ± 11 | 46 ± 16 | 33 ± 17 | 1.0000 |
Note: Data are mean ± SD.
*
P < 0.05 vs baseline.
Abbreviations: BP, blood pressure; CCBs, calcium channel blockers; SD, standard deviation.