Table 3.

Effects of candesartan and %change in BP on %change in CAVI

Analysis of covariance	Coefficient	Standard error	t-test	P value
Clinic systolic BP
Group (candesartan vs CCBs)	−2.373	2.896	−0.819	0.4246
%Change in systolic BP	0.358	0.229	1.562	0.1379
Group ×%change in systolic BP	0.116	0.229	0.507	0.6192
Clinic diastolic BP
Group (candesartan vs CCBs)	−1.120	3.528	−0.317	0.7551
%Change in diastolic BP	0.148	0.346	0.427	0.6748
Group ×%change in diastolic BP	0.332	0.346	0.959	0.3517
24-h ambulatory systolic BP
Group (candesartan vs CCBs)	−14.855	1.998	−7.433	0.0176
%Change in systolic BP	−1.237	0.141	−8.751	0.0128
Group ×%change in 24-h systolic BP	0.264	0.141	1.866	0.2031
24-h ambulatory diastolic BP
Group (candesartan vs CCBs)	−19.870	3.728	−5.330	0.0334
%Change in diastolic BP	−1.825	0.245	−7.453	0.0175
Group ×%change in 24-h diastolic BP	0.258	0.245	1.055	0.4019
BP variability
Group (candesartan vs CCBs)	−7.478	2.413	−3.099	0.0903
%Change in variability of BP	−0.013	0.099	−0.128	0.9100
Group ×%change in variability of BP	0.365	0.099	3.691	0.0662
Nocturnal decrease
Group (candesartan vs CCBs)	−7.048	6.557	−1.075	0.3949
%Change in nocturnal decrease	0.036	0.78	0.464	0.6885
Group ×%change in nocturnal decrease	0.036	0.078	0.020	0.9861
Morning surge
Group (candesartan vs CCBs)	−8.894	4.558	−1.951	0.1903
%Change in morning surge	−0.083	0.088	−0.948	0.4432
Group ×%change in morning surge	0.064	0.088	0.724	0.5441

Abbreviations: BP, blood pressure; CAVI, cardio-ankle vascular index; CCBs, calcium channel blockers.