Figure 3. Differential expression of mechanically-evoked currents in IB4 positive and negative neurons from wild type mice.
A. Percentage of small neurons responding to mechanical stimulation with either Slowly Adapting (SA) currents or Transient currents. More IB4 negative neurons responded to mechanical stimuli than IB4 positive neurons (* p<0.05, Fisher's exact test). SA currents were expressed predominantly by IB4 negative neurons; few were found in IB4 positive neurons. B. The average magnitude of the SA currents in IB4 negative neurons was much larger than the one SA current found in an IB4 positive neuron. In contrast, the magnitude of the Transient currents in IB4 positive and negative neurons was similar. Bars represent mean ± SEM.
