Figure 3. Differentially expressed genes within enriched domains in CPF, DZN and combination.
Major functional groups represented in all the treatments: CPF (cyan circle), DZN (orange circle) and a combination of both (blue circle). The number of genes that show a functional domain are shown in each case, indicating the common regulated genes. Only functional domains common and significant (p-value<0.01, hypergeometric test) within the three treatments are shown. Functional domain categories were extracted from defined proteins domains in Wormbase release 190 using BioMart. Domains description: IPR001128 = Cytochrome P450; IPR001747 = Lipid transport protein, N-terminal; IPR001846 = von Willebrand factor, type D; IPR002213 = UDP-glucuronosyl/UDP-glucosyltransferase; IPR003366 = CUB-like region.
