Table 2.
Summary of the pathological classification of glioma in index patients and affected relatives
| Index case | Relative | ||||||
|---|---|---|---|---|---|---|---|
| Glioma classification | WHO grade | N | Male | Median age (Years) |
N | Male | Median age (Years) |
| Pilocytic astrocytoma (PA) | I | 2 | 0 | 26 | 3 | 1 (33%) | 6 |
| Astrocytoma (A) | II | 19 | 5 (26%) | 40 | 25 | 12 (48%) | 34 |
| Oligodendroglioma (O) | II | 15 | 6 (40%) | 47 | 10 | 8 (80%) | 40 |
| Mixed oligoastrocytoma (OA) | II | 7 | 5 (71%) | 45 | 6 | 4 (67%) | 43 |
| Ependymoma (E) | II | 1 | 0 | 22 | 2 | 1 (50%) | 16 |
| Giant cell glioblastoma (GCG) | II | 1 | 1 (100%) | 40 | |||
| Anaplastic astrocytoma (AA) | III | 8 | 4 (50%) | 41 | 10 | 6 (60%) | 45 |
| Anaplastic oligodendroglioma (AO) | III | 4 | 2 (50%) | 59 | 9 | 8 (89%) | 60 |
| Anaplastic ependymoma (AE) | III | 2 | 0 | 48 | |||
| Glioblastoma multiforme (GBM) | IV | 41 | 18 (44%) | 54 | 66 | 37 (56%) | 58 |
| Glioma, unclassified (G-U) | 1 | 0 | 5 | 6 | 0 | 38 | |
| Optic nerve glioma (ONG) | 1 | 1 (100%) | 0.5 | ||||