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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Fam Cancer. 2010 Sep;9(3):413–421. doi: 10.1007/s10689-010-9346-5

Table 3.

Sequence variants identified in p16INK4A/p14ARF and p53

Gene Nucleotide change1 db SNP minor allele frequency2 Protein change Minor allele frequency
in the 101 cases (n)*
P16INK4A/P14ARF 19652 C>T - synonymous 0.005 (1)
rs3731249: 23575 G>A 0.017 A148T 0.030 (6)
rs11515: 26292 G>C 0.125 synonymous 0.129 (26)
rs3088440: 26332 C>T 0.103 synonymous 0.054 (11)
P53 rs1042522: 11392 C>G 0.233 P72R 0.262 (53)
11432 T>C - synonymous 0.005 (1)
12407 G>A - R158H 0.005 (1)
rs1800372 12654 A>G 0.016 synonymous 0.025 (5)
1

Nucleotide position is taken from the GenBank reference file, dbSNP accession number shown where available.

2

In Caucasians.

*

P-values for comparison of minor allele frequencies in cases with those obtained from dbSNP all >0.1.