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Pharmacokinetic parameters of Azurin p28 intravenously administered to mice (n= 4 per time point)
| Parameter | Dose (mg/kg) 480 |
|---|---|
| Cmax (μg/ml) | 2473 |
| Tmax (min) | 2 |
| T1/2α (min) | 2 |
| T1/2β (hours) | 0.23 |
| t1/2γ (hours) | 34.1 |
| AUC0-t (hr μg/ml)b | 278 |
| Clearance (ml/kg/hr)b | 1727 |
| Vdss (ml/kg) | 4084 |
Parameters were calculated from compartmental analysis of the data, except where indicated.
Calculated from non-compartmental analysis of the data
