Figure 1. Western blot analyses of tyrosine hydroxylase [TH] and dopamine transporters [DAT] in striata [A] and inferior frontal gyri [IFG] [B] from control [Cont], PD and PDD groups.
Tissue lysates were prepared as described under Materials and Methods, and analyzed by Western blots using antibodies against TH and DAT. Blots are from representative experiments, while the graph is a summary of quantitation of protein levels normalized against β-actin from striata of 17 PD cases, 18 with PDD and 22 controls and while IFG are from 9 PD cases, 7 PDD and 9 controls. * denotes p<0.01 for PD and PDD groups compared to controls, while † denotes p<0.01 for PDD compared to PD.