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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Pain. 2010 Aug;150(2):290–301. doi: 10.1016/j.pain.2010.05.005

Figure 5. TRPA1 is required for the induction of ATF3 expression by low doses of formalin.

Figure 5

(A-C) In wild-type mice, intraplantar injection of formalin induces expression of ATF3 (red) in large numbers of DRG neurons in a dose-dependent manner. (D-F) The expression induced by the low dose (D), but not high doses of formalin (E, F), was blocked in TRPA1 null mice. Calibration bar 200μm.