Table 4.

Association between fructose consumption and liver histology of NAFLD in different age groups

	Younger group (< 48 years old)				Older group (> = 48 years old)
	Adjusted (Model 1)		Adjusted (Model 2)		Adjusted (Model 1)		Adjusted (Model 2)
	OR [95% CI]	p-value	OR [95% CI]	p-value	OR [95% CI]	p-value	OR [95% CI]	p-value
Steatosis
Fructose consumption
< 7 servings	-	-	-	-	-	-	-	-
> = 7 servings	1.1 [0.6, 2.0]	0.72	1.0 [0.6, 1.9]	0.95	0.3 [0.1, 0.6]	0.0009	0.2 [0.1, 0.5]	0.0008
Lobular inflammation
Fructose consumption
< 7 servings	-	-	-	-	-	-	-	-
> = 7 servings	0.7 [0.4, 1.3]	0.24	0.9 [0.5, 1.8]	0.83	2.1 [1.0, 4.8]	0.07	2.5 [1.0, 6.2]	0.05
Ballooning
Fructose consumption
< 7 servings	-	-	-	-	-	-	-	-
> = 7 servings	1.3 [0.7, 2.3]	0.40	1.5 [0.8, 2.8]	0.19	2.1 [0.9, 4.5]	0.07	2.5 [1.0, 6.0]	0.05
Fibrosis
Fructose consumption
< 7 servings	-	-	-	-	-	-	-	-
> = 7 servings	2.5 [1.4, 4.4]	0.003	3.2 [1.7, 6.1]	0.0003	2.1 [0.1, 4.3]	0.05	3.2 [1.4, 7.4]	0.006

Fructose consumption is expresses as reported servings per week. OR (cumulative odds ratio) and p-values were derived from ordinal logistic regression models (Model 1: adjusted for age, gender, BMI, Hispanic ethnicity, and total calorie intake; Model 2: adjusted for age, gender, BMI, Hispanic ethnicity, total calorie intake, triglycerides, HDL-cholesterol, LDL-cholesterol, uric acid, and HOMA-IR.