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. 2010 Jul 26;107(32):14304–14308. doi: 10.1073/pnas.1001910107

Fig. 2.

Fig. 2.

Organization of the germline VLRC locus. (A) Structure of the germline VLRC gene of the Japanese lamprey (drawn to scale) and the schematic germline structures of other known VLR genes (not drawn to scale). (B) Organization of the sea lamprey VLRC locus. Two 5′-LRRCT-encoding modules, designated modules 1 and 2, are located downstream of the germline VLRC gene. This information is based on the analysis of contig 377 in the Pre Ensembl genome database. (C) The 5′-LRRCT of VLRC shows only limited diversity; basically only two major types of sequences were observed. One type represented by Lj1VLRC2 has a sequence identical or nearly identical to the 5′-LRRCT sequence located in the germline VLRC gene (LjgVLRC). The other type falls into two closely related subtypes represented by Lj1VLRC4 and Lj1VLRC16; the sequences of these clones are very similar to those of modules 1 and 2, respectively. “.” and “-” indicate identity with the top sequence and absence of residues, respectively. Clones are identified by the species name, followed by the animal number, gene name, and clone number. Thus, Lj1VLRC2 indicates a VLRC clone 2 isolated from Japanese lamprey individual 1.