Figure 1. Selectivity and affinity comparison of TD05 before and after Ce6 conjugation.


(Top) Flow cytometry analysis of FITC labeled TD05 with myeloid leukemia cell lines K-562, NB-4 and HL 60. TD05 only binds with target Ramos. (Bottom): Competitive binding of TD05 with Ramos cells for TD05 before and after Ce-6 conjugation. Shift to lower fluorescence after competitive binding indicates that both probes bind to the cells with similar affinities.