Table 2.

Sensitivity and specificity of individual signs and symptoms for AIDS deaths in Manicaland and Kisesa cohorts, stratified at age 45 years

Symptom	Train		Test
	Manicaland phase I		Manicaland phase II		Manicaland phase II				Kisesa
	15–44 years (n=237)		15–59 years (n=102)		15–44 years (n=180)		45–59 years (n=38)		15–44 years (n=158)		45–59 years (n=39)
	Se	Sp	Se	Sp	Se	Sp	Se	Sp	Se	Sp	Se	Sp
Weight loss	9	100	10	99	12	98	0	91	10	96	23	84
Herpes zoster	12	93	18	95	24	98	19	100	14	97	8	100
Jaundice	19	93	4	97	4	100	0	100	5	99	8	96
Vaginal tumours	6	94	6	94	3	100	0	100	0	100	0	96
Wasting	19	93	19	95	15	95	13	100	16	95	8	100
ARTI	11	95	10	95	8	95	13	100	5	96	0	88
Abscesses or sores	24	90	24	92	29	98	32	100	19	96	8	100
Oral candidiasis	38	86	37	89	45	86	26	91	40	92	15	100
Diarrhoea	17	95	17	92	29	93	23	100	10	92	8	88
Recent TB*	27	86	28	88	47	82	32	100	5	99	8	96

ARTI, acute respiratory tract infections; Se, sensitivity; Sp, specificity; TB, tuberculosis.

^*Recent tuberculosis is shown for information but was not included in the final algorithm due poor specificity.