Table 1.

Table 1a. Baseline Levels of Serum Biomarkers, by Treatment Group, for Markers with High Frequency of Detection.
	Treatment Group (N = 402)	Control Group (N = 394)	P value
CRP, pg/ml	0.76 (0.46)*	0.75 (0.46)	0.81†
PGE2, pg/ml	2.27 (0.51)	2.28 (0.49)	0.80
MMP-9, μg/ml	−0.24 (0.29)	−0.23 (0.28)	0.62
Fibrinogen, pg/ml	1.23 (0.24)	1.25 (0.25)	0.35
Endotoxin, ETX units	1.79 (1.09)	1.77 (1.11)	0.77

Table 1b. Presence of Serum Biomarkers at Baseline, by Treatment Group, for Markers with Low Frequency of Detection.
	Treatment Group (N = 402)	Control Group (N = 394)	P value
IL-1β	23 (5.7%)§	29 (7.4)	0.39**
IL-6	27 (6.7)	28 (7.1)	0.89
IL-8	16 (4.0)	8 (2.0)	0.15
TNF-α	28 (7.0)	32 (8.1)	0.59

^*Mean (standard deviation) of common log (base 10) for CRP, PGE2, MMP9, and Fibrinogen

^†From two-sample t-test

^§Number (percent) of samples above the lower limit of detection

^**From Fisher’s Exact Test