Table 1.
Proteins that influence budding of filoviruses.
| Virus | Budding protein | Viral proteins that affect budding |
Host proteins that promote budding |
Host proteins that inhibit budding |
Ref. |
|---|---|---|---|---|---|
| Ebola | VP40 (PTAPPEY) |
GP | Tsg101 | ISG15 | [15–17,19,20,24,49,66–68,70] |
| NP | Nedd4 | Tetherin | [15,21,31,49,82,84,92,93] | ||
| VP24 | VPS4A/B | [49,94–96] | |||
| VP35 | Sec 24 | [25,70] | |||
| Marburg | VP40 (PPPY) |
GP NP VP24 VP35 |
Tsg101 Nedd4 VPS4A/B |
Tetherin | [18,19,26,27,31,47,48,57, 78,79,82,83,88] |
GP: Glycoprotein; ISG: Interferon-stimulated gene; NP: Nucleoprotein; Tsg: Tumor susceptibility gene; VPS: Vacuolar protein sorting.