Table V.

Summary of nickel content in lungs after short-term exposures to nickel hydroxide nanoparticles.

Exposure Group	Ni content- 0.5 h PE (ng Ni/g of tissue)	Ni content- 24 h PE (ng Ni/g of tissue)	Ni content- 48 h PE (ng Ni/g of tissue)
Control	__	8.95 ± 5.15	__
Low	285.8 ± 47.03*	86.1 ± 26.5*	60.7± 8.82*
Mid	2200.0 ± 146.6*	1210.0 ± 169.2*	ND
High	4200.3 ± 384.3*	2270.0 ± 42.2*	1538.5 ± 17.5*

Abbreviations: PE, post-exposure; ND, not determined.

Reported values are averages of individually measured lung samples ± SEM; n = 3–4 for Ni-exposed mice and n = 3 for controls.

Asterisks indicate a statistically significant difference between nickel exposed and control groups (*P<0.05).