Table VI.

Summary of nickel content in lungs after long-term studies to nickel hydroxide nanoparticles.

Exposure Duration	Ni content- 24 h PE (ng Ni/g of tissue)
Control	17.9 ± 9.74
1w	147.8 ± 7.96*
3m	558.8 ± 1.31*
5m	925.2 ± 27.7*

Abbreviations: PE, post-exposure.

Reported values are averages of individually measured lung samples (n=3–4 for Ni-exposed mice and n=3 for controls).

Asterisks indicate a statistically significant difference between nickel exposed and control groups (*P<0.05).

Concentrations for 1 w, 3 m, and 5 m exposures were 124.0, 129.3, and 124.5 µg/m³ (78.6, 82.0, 79.0 µg Ni/m³), respectively.