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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: HIV Ther. 2010 Jul 1;4(4):483–504. doi: 10.2217/HIV.10.28

Table 4.

Select inhibitory natural killer-cell receptors, their ligands and function.

Receptor Ligand Function
IL-T2/LIR-1 (CD85j) HLA class I Survey loss of HLA I
KIR3DL1 HLA-B Survey loss of HLA I
KIR3DL2 HLA-A Survey loss of HLA I
KIR2DL1, 2/3 (CD158a,b) HLA-C Survey loss of HLA I
NKG2A (CD159a/CD94) HLA-E Survey loss of HLA I
KLRG Cadherins Survey loss of tissue integrity
Siglec-7,9 (CD328,329) Sialic acid ?
LAIR-1(CD305) Collagen Control extracellular activation

KIR: Killer cell immunoglobulin-like receptor.