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. Author manuscript; available in PMC: 2011 Jul 15.
Published in final edited form as: Bioorg Med Chem. 2010 Jun 1;18(14):5114–5122. doi: 10.1016/j.bmc.2010.05.068

Scheme 1.

Scheme 1

Reagents and conditions. (a) ClC(S)N(CH3)2, Dabco, DMF, 50 °C, 5 h; (b) no solvent, heating of fused substrates, microwaves; (c) NaOH, EtOH/H2O,65 °C; (d) (3,4,5-trimethoxyphenyl)-2-bromo-ethanone, K2CO3, (CH3)2CO, rx; (e) C6H5CH2SH, KOH, DMF; (f) AlCl3, C6H6.