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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: J Immunol. 2009 Oct 14;183(9):5738–5747. doi: 10.4049/jimmunol.0901563

Figure 7.

Figure 7

RANKL−/− mice have fewer germinal centers in their PP follicles and lower levels of fecal IgA. A, RANKL−/− PP on a mixed C57BL/6 and BALB/c background have fewer and less developed germinal centers identified by GL7+ cells than control PP. B, Fecal IgA concentrations (mean ± S.D.) measured by ELISA were consistently decreased in RANKL−/− mice compared to littermate controls based on analysis of samples from 5 to 16 mice of each genotype in each age range tested. *, p < 0.01; **, p < 0.001 (compared to control mice by t-test).