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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Bioorg Med Chem. 2010 Jun 22;18(16):6099–6108. doi: 10.1016/j.bmc.2010.06.053

Figure 6.

Figure 6

Optimization of the anti-Hdmx inhibitor using a focused library approach. (A) Chemical structures of RWF tripeptide variants with modified termini. (B) Accumulated inhibition profile of the library members at 320 μM (See Table S3 for % inhibition ± SD values). Abbreviations used: i-Pr = isopropyl, i-Bu = isobutyl, Ph = phenyl, Cbz = carbobenzyloxy, Bn = benzyl.