Table 3.

List of Primary, Secondary and Exploratory Outcomes and Planned Analyses

	Description (analysis)
Primary outcome
Osteoporosis medication possession ratio at 12 months	Percentage of total days with osteoporosis medication available (linear regression)
Secondary outcomes
Osteoporosis medication possession ratio at 18 and 24 months	See above
Osteoporosis medication persistence at 12, 18, and 24 months	Months until first 90 day gap without available osteoporosis medication available (survival analysis)
Fractures at 12 months	Fracture rate (Cox proportional hazard regression)
Exploratory outcomes
Nursing home admissions at 12 months	Nursing home admission rate (Cox proportional hazard regression); number of days in nursing home (linear regression)
Health care resource utilization at 12 months	Cost of direct care (linear regression)
Survival at 12 months	Mortality rate (Cox proportional hazard regression)