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. 2010 Jul 8;25(9):2374–2386. doi: 10.1093/humrep/deq123

Table III.

Relationships between the proportion of normal oocytes calculated over the number of diagnosed oocytes and the following variables: female age, type of stimulation (GnRH agonist or antagonist), use of clomiphene (yes or no), causes of infertility (male, endometriosis, idiopathic, tubal, ovarian, recurrent abortions), indication to FISH–PB (female age, abortions, previous failed cycles, no indication, multiple indications), number of collected oocytes, number of collected MII oocytes, number of FSH international units per oocyte, number of FSH international units per MII oocyte, clinical pregnancy.

Relationship Level of intersection with the Y ordinate axis Regression coefficients Significance of each regression coefficients of dependent variables
Determining factors (t) pρ

  • Normal oocytes/diagnosed oocytes

  • female age

  • type of stimulation (agonist or antagonist)

  • clomiphene (yes/no)

  • causes of infertility (male, endometriosis, idiopathic, tubal, ovarian, abortions)

  • indication to FISH–PB (female age, abortions, previous cycles, no indication, multiple indications)

  • -number of collected oocytes

  • number of collected MII oocytes

  • FSH units/oocyte

  • FSH units/MII oocyte

  • clinical pregnancy

 Independent variable (predictor) Normal oocytes/diagnosed oocytes −9115
Dependent variables Female age −11.130 89.001 <0.01
Type of stimulation (agonist/antagonist) 0.478 1.244 NS
Clomiphene (yes/no) −0.654 0.112 NS
Cause of infertility: male 0.111 0.112 NS
Cause of infertility: endometriosis −12.223 10.117 <0.01
Cause of infertility: idiopathic 1.212 2.117 NS
Cause of infertility: tubal 0.017 1.238 NS
Cause of infertility: ovarian −7.116 9.118 <0.01
Cause of infertility: abortions −11.878 8.118 <0.01
Indication to FISH–PB: female age −4.144 11.320 <0.01
Indication to FISH–PB: abortions −5.116 8.115 <0.01
Indication to FISH–PB: number of previous cycles −1.134 5.091 <0.05
No indication to FISH–PB 0.011 0.114 NS
Multiple indications to FISH–PB −2.119 12.338 <0.01
Number of collected oocytes −0.012 0.002 NS
Number of collected MII oocytes 9.678 11.167 <0.01
Number of FSH units/oocyte −8.156 9.118 <0.01
Number of FSH units/MII oocyte −8.556 9.113 <0.01
Clinical pregnancy 6.445 9.667 <0.01

NS, not significant; FISH–PB, chromosomal analysis of PB by FISH; IU, international Units; MII oocyte, metaphase II oocyte.