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Concentration of cortical PGE2 following MCAO and reperfusion is dependent on cPLA2α. PGE2 was measured in cortical homogenate from the ipsilateral and contralateral hemispheres after A: 2 hours MCAO or sham operation and B: 2 hours of MCAO and 6 hours reperfusion. Results are expressed as normalized for each lipid extraction and assay. * P < 0.05; ** P < 0.01 n = 3 - 4 each condition.
