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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Hear Res. 2010 Jun 2;268(1-2):172–183. doi: 10.1016/j.heares.2010.05.019

Figure 6. CD spectra of rOC90. The CD spectra were generated by numerical deconvolution analysis.

Figure 6

The spectra indicate prevalence of alpha helical secondary structure, with minima at 208 nm and 222 nm, and one maximum at 192 nm. Exposure to Ca2+ or HCO3- ions induced characteristic changes of the secondary structure of 5 μM rOC90. 7.5 mM Ca2+ (red) causes a slight decrease in alpha helical and increase in beta structure, while 4 mM HCO3- (green) leads to an increase of both alpha and beta structure. Application of Ca2+ and HCO3-1 in combination resulted in an 11.6% increase in alpha helical structure (see Table I).