Table 2. Clinical laboratory parameters.
Alcoholic Liver Disease (ALD) (n = 40) | Active drinkers w/o liver disease (AD) (n = 26) | Healthy Subjects (HS) (n = 28) | Overall p value | |
---|---|---|---|---|
WBC K/mm3 [4.5-11] | 6.3 (3.6-15.4) | 6.1 (4-9.5) | 5.7 (4.5-10.4) | 0.06 |
Hb mg/dL [12-16] | 13 (9.2-17.2)a | 14 (11-16.5)b | 14.5 (11.8-17.3)b | <.02 |
Platelets K/mm3 [130-400] | 206 (55-403)a | 254 (167-422)b | 242 (167-449)a, b | <.02 |
AST U/L [15-37] | 70.5 (47-350)a | 28 (15-37)b | 26 (14-37)b | <.0001 |
ALT U/L [5-37] | 38 (14-211)a | 24 (14-33)b | 26 (12-36)b | <.0001 |
Total bilirubin mg/dL [0.3-1.3] | 1.4 (0.5-7.3)a | 0.7 (0.5-1.3)b | 1 (0.6-1.3)b | <.0001 |
Alkaline Phosphatase U/L [35-115] | 121 (52-425)a | 62 (44-89)b | 62 (34-99)b | <.0001 |
Albumin g/dL [3.2-4.6] | 3.4 (2.4-4.3)a | 4 (3.4-4.7)b | 4 (3.1-4.5)b | <.0001 |
INR [0.75-1.19] | 1.1 (0.9-1.8)a | 0.9 (0.8-1.1)b | 1 (0.9-1.1)b | <.0001 |
Creatinine mg/dL [0.44-1.4] | 0.8 (0.5-1.39) | 0.9 (0.62-1.2) | 0.9 (0.6-1.2) | 0.06 |
%CDT | 3.9 (1.9-8.7)a | 3.8 (1.6-6.9)a | 2.6 (1.4-3.8)b | <.02 |
Folate ng/mL [3.5-16.1] | 16.5 (0.4-20)a | 14.8 (4.8-20)a | 20 (9-20)b | <.05 |
Vitamin B12 pg/mL [200-600] | 667 (288-1733)a | 473 (220-2000)b | 505 (322-1850)b | <.02 |
Vitamin B6 nmol/L [15-120] | 44.5 (8.6-187.4)a | 71.7 (22.4-195.8)b | 83.6 (15-299)b | <.02 |