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. Author manuscript; available in PMC: 2011 Sep 30.
Published in final edited form as: Virology. 2010 Jul 3;405(2):269–279. doi: 10.1016/j.virol.2010.06.006

Figure 7.

Figure 7

HSV-2 gE is required for targeting envelop and capsid proteins into axons. SCG neurons were infected with 105 PFU of WT, rgE2-del or gE2-del virus and at 18 h post infection, neurons were stained with antibodies to viral antigens gD (red, first column), VP26 (red, fourth column), to SCG neurofilaments (green, second and fifth columns), and as merged images (third and sixth columns). White arrows indicate viral antigens in axons. Most cells are infected as separate neurons; however, some neurons are in clusters (infected with WT or rgE2-del virus and stained for VP26). Note the total absence of gD or VP26 antigen (red) in SCG axons infected with gE2-del virus. Magnification is 400X.