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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Mol Cell Neurosci. 2010 Jun 21;45(2):180–191. doi: 10.1016/j.mcn.2010.06.009

Fig. 4.

Fig. 4

Cross-validation for the expression of proliferation index markers in relevance to neurogenesis around the subventricular and subgranular zones (SVZ, SGZ). Panels (A-C) show partial colocalization of PCNA in DCX+ cells at the SVZ. Panels (D-F) show Ki67 expression in heavy but not light reactive PCNA+ nuclei in the SVZ. Panels (G-I) show Ki67 expression in DCX+ cell clusters at the SGZ. Panels (J-P) show partial colocalization of BrdU in Ki67+ (J-M) and PCNA+ (N-P) cells around the SVZ at 3 hours after a single BrdU injection. At 7 days post-BrdU administration, BrdU labeling is found in DCX+ cells at the SGZ that have well-formed dendrites extending into the molecular layer (Q-S). Scale bar in (A) = 25 μm applying to (B-I, N-S), equivalent to 100 μm for (J-M).