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Survival curve of mice treated with COX inhibitors. cPLA2+ / + and cPLA2− / − mice were placed on diets containing celecoxib (0.15%), rofecoxib (0.0075%), sulindac (0.015%), or aspirin (0.05%), and mortality was recorded. The graph shows the percentage of surviving mice following the start of administration (day 0) of (A) celecoxib, (B) sulindac, (C) rofecoxib, or (D) aspirin. The data represent a minimum of 10 mice per group.
