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Effect of DTT on organochalchogens-induced mitochondrial dysfunction. Effect of DTT (10μM) on Ebs (5μM)-induced mitochondrial depolarization (A) or swelling (B). Effect of DTT (80μM) on (PhSe)2 (20μM)-induced mitochondrial depolarization (C) or swelling (D). The mitochondria (0.5 mg/ml), organochalchogens, or 2,4 DNP (100μM) were added where indicated by arrows in medium containing DTT. The traces are representative of three independent experiments.
