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. 2010 Sep;24(9):3160–3170. doi: 10.1096/fj.09-152587

Figure 6.

Figure 6.

PDT effects of bacteriochlorin 3 on GFP-positive B16F10 melanoma tumors. A) B16F10-GFP subcutaneous tumor on d 7 before PDT treatment. B) B16F10-GFP tumor on d 13 after PDT treatment. C) In vivo fluorescence imaging of B16F10-GFP tumor immediately after inoculation. D) GFP signal from tumor on d 7 before PDT. E) Two-color imaging of bacteriochlorin 3 (red) and B16F10-GFP tumor (green) 15 min postintravenous injection on d 9. F) Control tumor on d 13. G) PDT-treated tumor on d 13. H) Control tumor on d 23. I) PDT-treated tumor on d 23. J) Regrowth of a PDT-treated tumor on d 26. K) Mean tumor volumes of control and PDT-treated B16F10-GFP melanoma tumors. L) Survival analysis of in vivo PDT effectiveness with bacteriochlorin 3 on B16F10-GFP tumors: solid line, no treatment (n=8); dotted line, PDT (n=10). P < 0.01 (log rank test).