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Ratios of generation of IL-6, TNF-α, and IP-10 chemokine by differentiated monocytes from healthy old (group I) and young subjects. Columns and bars depict mean ± sd values for supernates harvested at 6 h (hatched columns) and 24 h (open columns). Statistical significance of increases above and decreases below the level of 1 (no difference between young and old) was calculated by the Mann-Whitney nonparametric test. +P < 0.05; *P < 0.01; **P < 0.001.
