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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: J Cell Biochem. 2010 Aug 15;110(6):1279–1287. doi: 10.1002/jcb.22650

Fig. 3.

Fig. 3

Pygo2 is required for mammary epithelial stem/progenitor cell expansion and K14-ΔN-β-catenin-induced mammary hyperplasia. a: Reduced presence of K6+ progenitor cells in 8-week-old Pygo2-deficient mammary duct and ductal termini (inset). b: Carmine red-stained whole-mount mammary gland preparations from 3-week-old female mice, showing absence of TEB structures (arrows) in the mutant. c: Whole-mount carmine-stained mammary glands of 12-week-old K14-ΔN-β-catenin and K14-ΔN-β-catenin/K14-Cre/Pygo2floxed/− (SSKO) littermates (Gu et al., 2009; originally published in J Cell Biol 185:811– 826).