Figure 3.

Parameter dependence of the development of OD columns using a Hebbian learning rule with subtractive weight normalization (Eq. 6). Panels plot synaptic strengths in color as a function of cortical position, x, and simulated time steps as in Figure 2A. Explicitly mentioned parameters are changed, whereas the other parameters are as in the parameter set 1. The learning rule of Equation 6 is sensitive to parameter choices: with intracortical connections that are too weak, M_A = 1.0, the two eyes do not equalize even after the maturation of inhibition (A); with inhibition during the CP that is too weak, R = 1.0, the two eyes do not equalize (B); with too little noise, σ² = 3 Hz/τ, almost no OD shift is observed during the simulated MD (C). D, For balanced LTP and LTD, ρ = 1.0, no OD shift is observed after MD.