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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Psychopharmacology (Berl). 2010 May 19;211(2):141–148. doi: 10.1007/s00213-010-1875-y

Table 3.

Performance on selected psychomotor and cognitive tasks (mean±SEM) as a function of placebo, naltrexone dose, and marijuana strength

Naltrexone dose


Variable MJ strength 0 mg 12 mg 25 mg 50 mg 100 mg
DAT: average speed (cm/s) Inactive   7.3 (0.2)   6.6 (0.2)*   6.9 (0.2)*   6.7 (0.2)*   7.0 (0.2)*
Active   7.0 (0.2)   7.0 (0.2)   7.1 (0.2)   6.9 (0.2)   6.9 (0.2)
DSST:Total attempts Inactive 86.2 (1.8) 86.7 (1.7) 83.4 (1.7) 83.6 (1.8) 82.1 (1.6)*
Active 86.1 (1.7) 84.7 (1.6) 83.5 (1.6) 82.1 (1.4)* 83.0 (1.7)*
DRT: delayed recognition (% correct) Inactive 66.7 (5.1) 57.5 (5.3) 49.4 (5.4)* 60.9 (5.3) 63.2 (5.2)
Active 66.7 (5.1) 57.5 (5.3) 57.5 (5.3) 59.8 (5.3)* 66.7 (5.1)

Data are presented as average values (±SEM) across post-smoking time points (30, 75, and 180 min after smoking). Significant differences between active and placebo naltrexone are indicated (*p≤0.01)