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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Mol Cancer Res. 2010 Jul 27;8(8):1095–1104. doi: 10.1158/1541-7786.MCR-10-0195

Figure 3. Tumorigenesis in CAC;APC580S/+ mice.

Figure 3

(A) Representative images of colorectal tumors (arrow) in CAC;APC580S/+ mice without DSS (a) or after 2% DSS for 7d (b) or 5d (c). Bar =1 cm. (B) Distribution and size of tumors in the lower bowel of CAC;APC580S/+ mice without DSS (a) or after 2% DSS for 5d or 7d (b). (C) Examples of H&E stained sections representing different colonic lesions seen in CAC;APC580S/+ mice. (a) microadenoma (arrow), Bar = 100 μm, (b, c) adenomas, Bar = 1 mm. N, normal-looking tissue. A, adenomatous tissue. (D) Examples of H&E stained sections representing simple adenomas from CAC;APC580S/+ mice without DSS treatment (a) and complex, multiple adenomas from DSS treated CAC;APC580S/+ mice. Bar = 1 mm.

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