Table 3.
Mouse genes on Chr 17 homologous to genes in human QTL on Chr 18
| Symbol | ID (MGI) | Start | Coding region | Noncoding regions | ||||
|---|---|---|---|---|---|---|---|---|
| Synonymous | Nonsynonymous | Upstream | Downstream | mRNA-UTR | Intron | |||
| Vapa | 1353561 | 65929396 | 1 (1) | |||||
| Txndc2 | Txndc2 | 65986854 | ||||||
| Rab31^ | 1914603 | 66001069 | 1 | 234 (54) | ||||
| Ppp4r1^ | 1917601 | 66169485 | 1 (1) | (5) | (4) | 1 (1) | 135 (38) | |
| Ralbp1#^ | 108466 | 66197781 | 3 (3) | 1 | (5) | (4) | 3 (1) | 101 (39) |
| Twsg1^ | 2137520 | 66272406 | 3 (3) | 15 (11) | ||||
| Ankrd12 | 1914357 | 66316841 | 7 (4) | |||||
| Ndufv2 | 1920150 | 66428135 | 5 (3) | |||||
| Rab12 | 894284 | 66843852 | ||||||
| Ptprm | 102694 | 67016883 | 1 (1) | 2428 (647) | ||||
| Lrrc30 | 2685172 | 67981021 | (1) | |||||
| Lama1# | 99892 | 68046605 | 9 (1) | 5 (1) | 242 (21) | |||
| Arhgap28 | 2147003 | 68192053 | 1 | |||||
| Epb4.1l3 | 103008 | 69506150 | (2) | 14 (11) | ||||
| Zfp161^ | 1195345 | 69732390 | (1) | 2 | 1 | |||
| Dlgap1#^ | 1346065 | 70318413 | 1 (1) | 1 | 5 | 2428 (216) | ||
| Tgif^ | 1194497 | 71193551 | (1) | 2 (1) | 2 (1) | |||
| Myl12b | 107494 | 71323260 | (3) | |||||
| Myom1#^ | 1341430 | 71368861 | 8 | 5 (1) | (1) | 3 | 417 (119) | |
| Lpin2^ | 1891341 | 71531900 | 2 (1) | (2) | 6 (6) | 88 (48) | ||
| Emilin2#^ | 2389136 | 71601516 | 11 (8) | 12 (3) | (3) | 4 | 375 (82) | |
| Smchd1^ | 1921605 | 71693829 | 1 (1) | (5) | 2 | 284 (125) | ||
| Ndc80#^ | 1914302 | 71845442 | 4 (3) | 1 (1) | 2 (1) | 86 (55) | ||
SNPs were retrieved from the Wellcome Trust Sanger Institute Mouse Genome Project and the MGI dbSNP Build 128 (in parenthesis). MGI IDs are indicated. The start site of the gene on mouse chromosome 17 was retrieved from Ensembl annotation of the NCBI Build 37. Synonymous SNPs are SNPs in the coding region with no amino acid change. Nonsynonymous SNPs are SNPs with an amino acid change. Upstream is the region 2 kb from the 5′ coordinate. Downstream is the region 2 kb downstream from the 3′ coordinate. mRNA-UTR indicates SNPs in the mRNA-untranslated region. Items in the Symbol column with no symbol means that there are no SNPs in the nonsynonymous coding regions or SNPs in the mRNA-UTR; # = nonsynonymous SNPs in the coding region; ^ = SNPs in the mRNA UTR. Genes with differential expression in B6 and A/J mice are indicated in bold