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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Nat Genet. 2010 Jul 11;42(8):698–702. doi: 10.1038/ng.625

Figure 2.

Figure 2

Analysis of associations within the MHC. The 292 SNPs from the MHC region with allelic Chi-squared P < 0.0001 are shown before (blue symbols) and after (red symbols) conditioning for HLA-B51. Blue symbols represent -log10 P (allelic Chi-squared test). Red symbols represent –log10 regressor P-values of the same markers from a logistic regression analysis with HLA-B51 specified as a covariate. The green horizontal line at –log10P = 7.301 corresponds to the genome-wide significance threshold of 5 × 10-8. The locations of HLA genes are shown above the association graph.