Table 3.
Sox2 expression according to pathologic characteristics in 104 stage I lung adenocarcinomas.
| Tumor Characteristic | n | Sox2 negative (%) |
Sox2 positive (%) |
P value | |
|---|---|---|---|---|---|
| AJCC classification* | 0.70 | ||||
| T1 | 52 | 27 (52) | 25 (48) | ||
| T2 | 51 | 24 (47) | 27 (53) | ||
| Pleural invasion† | 0.14 | ||||
| Present | 36 | 14 (39) | 22 (61) | ||
| Absent | 64 | 36 (56) | 28 (44) | ||
| Grade | 0.24 | ||||
| Well | 19 | 11 (58) | 8 (42) | ||
| Moderate | 55 | 23 (42) | 32 (58) | ||
| Poor | 30 | 18 (60) | 12 (40) | ||
| Predominant subtype | 0.72 | ||||
| Acinar | 53 | 25 (47) | 28 (53) | ||
| BAC | 14 | 6 (43) | 8 (57) | ||
| Papillary | 19 | 10 (53) | 9 (47) | ||
| Solid | 18 | 11 (61) | 7 (39) | ||
| TTF-1 expression | 0.76 | ||||
| Positive | 92 | 45 (49) | 47 (51) | ||
| Negative | 12 | 7 (58) | 5 (42) | ||
*
T classification could not be determined in one case.
†
The presence of pleural invasion could not be assessed in four cases.