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. Author manuscript; available in PMC: 2011 Jul 21.
Published in final edited form as: J Am Chem Soc. 2010 Jul 21;132(28):9653–9662. doi: 10.1021/ja100608w

Table 1.

Selected Binding Data for the Plant Lectins

Lectin Ligand1 Without BSA (1:0) With BSA (1:7) Inhibition data
App Kd
(nM)		 p-value2 App Kd
(nM)		 p-value2 IC50 (nM) p-value2
ConA Man6 49±29 108±10 38±14
Man-α 69±7 0.23 NB <0.0005 >758 <0.0005
Glc-α 113±15 0.04 NB <0.0005 >758 <0.0005
VVL-B4 Ac-A-TnThr-S-G-23 66±9 317±115 16±4
Ac-S-TnSer-S-G-22 132±44 0.17 ND <0.0005 650±39 0.002
Ac-V-Tn(Thr)-S-G-19 125±58 0.29 ND <0.0005 368±35 0.03
GA2di-37 164±27 0.04 ND <0.0005 172±2 0.001
RCA120 LacNAc (trimeric) 8.0±0.3 83±18 11.5±0.8
Lac 8.1±0.5 0.83 307±42 0.02 114±3 0.0005
1

For complete array data and apparent Kd values, see the Supporting Information.

2

Paired t-test. NB denotes no binding. ND (not determined) denotes some binding but apparent Kd too large to measure. Values have not been adjusted for valency. Complete binding data can be found in the supporting information.