Figure 3.
Coimmunoprecipitation of c-Abl with Gal-3. MDA-MB-435 cell lysates were immunoprecipitated using anti-galectin-3 (lanes 1,4,5), anti-TCF-4 (lane 2) and anti-β-catenin (lane 3) antibody and immunoblotted with anti-c-Abl, anti-TCF-4, anti-β-catenin and anti-galectin-3 polyclonal antibodies. Some cells were treated with sucrose and lactose (line 4,5 respectively). To confirm equal loading of immunoprecipitated proteins 15% of IP mixture was run on 10% SDS-PAGE and visualized with Coomassie blue stain.