Figure 6.
CB8-2 inhibits HIV replication in infected human PBMC. Donor derived human PBMCswere infected with HIV-1NL4-3 and incubated for 8 days respectively days in the presence or absence of a CB8-2 or an isotype control antibody. Culture supernatants were collected and virus output was determined by luciferase expression of TZM cells exposed to the culture supernatant. Results are represented as percent viral inhibition as compared to infected PBMC cells without antibody. The graph shows the level of inhibition of virus production in infected PBMCs by different concentrations of antibody.