TABLE 5.

Brain Krebs cycle and CoA intermediates

Values are means in μmol/g wet weight ± S.E. with n = 12 given in parentheses. CoA is given in nmol/g wet weight.

Substrate	Starch	Fat	Ketone ester
Citrate	0.205 ± 0.006	0.213 ± 0.005	0.229 ± 0.010
Isocitrate	0.0109 ± 0.0011	0.0100 ± 0.0006	0.0121 ± 0.0011
α-Ketoglutarate	0.138 ± 0.005	0.152 ± 0.006	0.142 ± 0.007
Succinyl-CoA nmol/g	0.836 ± 0.050	0.805 ± 0.120	0.930 ± 0.144
Succinate	0.077 ± 0.002	0.079 ± 0.004	0.078 ± 0.004
Fumarate	0.074 ± 0.003	0.078 ± 0.004	0.074 ± 0.004
l-Malate	0.195 ± 0.009	0.205 ± 0.011	0.180 ± 0.011
Calc Oxaloacetate	0.003 ± 0.0003	0.002 ± 0.0001	0.003 ± 0.0004
Acetyl-CoA nmol/g	6.86 ± 0.93	7.52 ± 0.75	6.23 ± 0.36
Malonyl-CoA nmol/g	0.970 ± 0.037	1.02 ± 0.10	1.20 ± 0.08a

^a p < 0.05 between ketone ester and starch as judged by Mann-Whitney U test.