. 2010 Jun 29;285(34):26088–26096. doi: 10.1074/jbc.M110.149963

TABLE 1.

Effects of MTSET on currents and magnitudes of Na⁺ self-inhibition in mutants containing γE234C alone or in combination with an additional mutation

I_MTSET/I was the ratio of the amiloride-sensitive current following 1 mm MTSET treatment for 2 min and the current before the treatment. I_ss/I_peak¹ and I_ss/I_peak² were obtained prior to and after MTSET treatment in the same oocyte, respectively. Values are mean ± S.E.

Channel	Oocytes	I_ss/I_peak¹	I_MTSET/I	I_ss/I_peak²
αβγE234C	5	0.40 ± 0.01	3.43 ± 0.07	0.72 ± 0.01
αβγE234C-H239R	4	0.89 ± 0.01^a	1.32 ± 0.02^a	0.93 ± 0.00^a
αβγE234C/R143A-Δ144–186	5	0.98 ± 0.02^a	1.23 ± 0.01^a	0.96 ± 0.01^a
αβS518KγE234C	5	0.96 ± 0.01^a	1.19 ± 0.03^a	0.96 ± 0.01^a

^a p < 0.01 versus αβγE234C.