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Comparison of skeletal defects among the mutants. The red arrow indicates that the eight ribs were attached the sternum in the IG-DMR(−/+) mutants. The blue arrow points the absence of the fifth ossification center in the Gtl2(+/−) mutants. The skeletal defect was absent in the IG-DMR(−/+)/Gtl2(+/−) double mutants.
