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. 2010 Jun 22;285(34):26558–26569. doi: 10.1074/jbc.M109.063255

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 4. — Effects of antimycin A (Ant. A) and cyclosporin A (CsA) on PEITC-mediated ROS generation. Effect of 1-h pretreatment with 10 μm antimycin A (A) or co-treatment with CsA (B) and PEITC on MitoSOX Red fluorescence in LNCaP and PC-3 cells. Results shown are mean ± S.E. Total sample size is n = 6–9 per group. As described under “Statistical Methods,” S.E. bars are estimated from the mixed effects ANOVA. Significantly different (*, p < 0.05, **, p < 0.01, and ***, p < 0.001) between the indicated groups by mixed effects ANOVA.