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. 2010 Aug 19;6(8):e1001051. doi: 10.1371/journal.ppat.1001051

Figure 5. IL-15 induced activation of HCMV and EBV-specific CD8 T cells.

Figure 5

A) PBMC of 4 healthy volunteers were incubated with IL-15 (10 ng/ml), IL-2 (20 U/ml), IL-7 (10 ng/ml), IFN-γ (100 U/ml), IFN- α (100 U/ml), TNF- α (100 U/ml). Cells were harvested at the indicated time points and frequency of CD38/HLA-DR expressing virus specific CD8 T cells was analyzed. B) Contour plots show the CD38/HLA-DR expression of EBV, HCMV or Influenza specific CD8 T cells after 48 hours of incubation with the indicated cytokines in a representative healthy subject.